Antibody–drug conjugates: Recent advances in linker chemistry

Antibody–drug conjugates (ADCs) are gradually revolutionizing clinical cancer therapy. The antibody–drug conjugate linker molecule determines both the efficacy and the adverse effects, and so has a major influence on the fate of ADCs. An ideal linker should be stable in the circulatory system and re...

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Detalles Bibliográficos
Autores principales: Su, Zheng, Xiao, Dian, Xie, Fei, Liu, Lianqi, Wang, Yanming, Fan, Shiyong, Zhou, Xinbo, Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727783/
https://www.ncbi.nlm.nih.gov/pubmed/35024314
http://dx.doi.org/10.1016/j.apsb.2021.03.042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727783/
https://www.ncbi.nlm.nih.gov/pubmed/35024314
http://dx.doi.org/10.1016/j.apsb.2021.03.042

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