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Leukotriene B4 Is a Major Determinant of Leukocyte Recruitment During Otitis Media

BACKGROUND: Pathogens of otitis media (OM) induce inflammatory responses in the middle ear (ME), characterized by mucosal hyperplasia, leukocyte infiltration, and inflammatory mediators, including arachidonic acid metabolites. We studied the role of the eicosanoid leukotriene B4 (LTB4) in OM. METHOD...

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Detalles Bibliográficos
Autores principales: Heo, Kyung Wook, Pak, Kwang, Kurabi, Arwa, Ryan, Allen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727869/
https://www.ncbi.nlm.nih.gov/pubmed/35004347
http://dx.doi.org/10.3389/fcimb.2021.768815