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Mechanisms of immune checkpoint inhibitor-mediated liver injury

The immune checkpoints, cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and programmed cell death protein-1/ligand-1 (PD-1/PD-L1) are vital contributors to immune regulation and tolerance. Recently immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy; however, they come with t...

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Detalles Bibliográficos
Autores principales: Shojaie, Layla, Ali, Myra, Iorga, Andrea, Dara, Lily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727893/
https://www.ncbi.nlm.nih.gov/pubmed/35024302
http://dx.doi.org/10.1016/j.apsb.2021.10.003