DNA-PK inhibition by M3814 enhances chemosensitivity in non-small cell lung cancer

A significant proportion of non-small cell lung cancer (NSCLC) patients experience accumulating chemotherapy-related adverse events, motivating the design of chemosensitizating strategies. The main cytotoxic damage induced by chemotherapeutic agents is DNA double-strand breaks (DSB). It is thus conc...

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Detalles Bibliográficos
Autores principales: Wang, Manni, Chen, Siyuan, Wei, Yuquan, Wei, Xiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727896/
https://www.ncbi.nlm.nih.gov/pubmed/35024317
http://dx.doi.org/10.1016/j.apsb.2021.07.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727896/
https://www.ncbi.nlm.nih.gov/pubmed/35024317
http://dx.doi.org/10.1016/j.apsb.2021.07.029

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