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Inhibition of SOS Response by Nitric Oxide Donors in Escherichia coli Blocks Toxin Production and Hypermutation

BACKGROUND: Previous reports have differed as to whether nitric oxide inhibits or stimulates the SOS response, a bacterial stress response that is often triggered by DNA damage. The SOS response is an important regulator of production of Shiga toxins (Stx) in Shiga-toxigenic E. coli (STEC). In addit...

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Detalles Bibliográficos
Autores principales: Crane, John K., Burke, Sarah R., Alvarado, Cassandra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727911/
https://www.ncbi.nlm.nih.gov/pubmed/35004358
http://dx.doi.org/10.3389/fcimb.2021.798136