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Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control multiple cellular components and lung metastasis in vivo

With the understanding of microRNA (miRNA or miR) functions in tumor initiation, progression, and metastasis, efforts are underway to develop new miRNA-based therapies. Very recently, we demonstrated effectiveness of a novel humanized bioengineered miR-124-3p prodrug in controlling spontaneous lung...

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Detalles Bibliográficos
Autores principales: Deng, Linglong, Petrek, Hannah, Tu, Mei-Juan, Batra, Neelu, Yu, Ai-Xi, Yu, Ai-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727917/
https://www.ncbi.nlm.nih.gov/pubmed/35024318
http://dx.doi.org/10.1016/j.apsb.2021.07.027