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Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control multiple cellular components and lung metastasis in vivo
With the understanding of microRNA (miRNA or miR) functions in tumor initiation, progression, and metastasis, efforts are underway to develop new miRNA-based therapies. Very recently, we demonstrated effectiveness of a novel humanized bioengineered miR-124-3p prodrug in controlling spontaneous lung...
Autores principales: | Deng, Linglong, Petrek, Hannah, Tu, Mei-Juan, Batra, Neelu, Yu, Ai-Xi, Yu, Ai-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727917/ https://www.ncbi.nlm.nih.gov/pubmed/35024318 http://dx.doi.org/10.1016/j.apsb.2021.07.027 |
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