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A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT

T cell immunoglobulin and ITIM domain (TIGIT) is a novel immune checkpoint that has been considered as a target in cancer immunotherapy. Current available bioassays for measuring the biological activity of therapeutic antibodies targeting TIGIT are restricted to mechanistic investigations because do...

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Detalles Bibliográficos
Autores principales: Fu, Zhihao, Liu, Hongchuan, Wang, Lan, Yu, Chuanfei, Yang, Yalan, Feng, Meiqing, Wang, Junzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727920/
https://www.ncbi.nlm.nih.gov/pubmed/35024316
http://dx.doi.org/10.1016/j.apsb.2021.09.011