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A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT
T cell immunoglobulin and ITIM domain (TIGIT) is a novel immune checkpoint that has been considered as a target in cancer immunotherapy. Current available bioassays for measuring the biological activity of therapeutic antibodies targeting TIGIT are restricted to mechanistic investigations because do...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727920/ https://www.ncbi.nlm.nih.gov/pubmed/35024316 http://dx.doi.org/10.1016/j.apsb.2021.09.011 |