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Chemical inducer of regucalcin attenuates lipopolysaccharide‐induced inflammatory responses in pancreatic MIN6 β‐cells and RAW264.7 macrophages

We previously isolated derrisfolin A, a novel rotenoid derivative, from the stems of Derris  trifoliata Lour. (Leguminosae). Here, we report that derrisfolin A induces the expression of endogenous regucalcin (RGN) protein in both pancreatic MIN6 β‐cells and RAW264.7 macrophages. Induction of RGN exp...

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Detalles Bibliográficos
Autores principales: Murata, Tomiyasu, Hashimoto, Kazunori, Kohno, Susumu, Takahashi, Chiaki, Yamaguchi, Masayoshi, Ito, Chihiro, Masataka, Itoigawa, Kojima, Roji, Hikita, Kiyomi, Kaneda, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727933/
https://www.ncbi.nlm.nih.gov/pubmed/34709731
http://dx.doi.org/10.1002/2211-5463.13321