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Overexpressed Smurf1 is degraded in glioblastoma cells through autophagy in a p62‐dependent manner

Homologous to E6AP C‐terminus (HECT)‐type E3 ubiquitin ligase SMAD‐specific E3 ubiquitin protein ligase 1 (Smurf1) was originally identified to ubiquitinate Smad protein in the TGF‐β/BMP signaling pathway. Recently, Smurf1 has been reported to promote tumorigenesis by regulating multiple biological...

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Detalles Bibliográficos
Autores principales: Han, Da, Li, Shengzhen, Xia, Qin, Meng, Xinyi, Dong, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727935/
https://www.ncbi.nlm.nih.gov/pubmed/34614303
http://dx.doi.org/10.1002/2211-5463.13310