Optimized two‐step electroporation process to achieve efficient nonviral‐mediated gene insertion into primary T cells

The development of gene editing technologies over the past years has allowed the precise and efficient insertion of transgenes into the genome of various cell types. Knock‐in approaches using homology‐directed repair and designer nucleases often rely on viral vectors, which can considerably impact t...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Ming, Tkach, Diane, Boyne, Alex, Kazancioglu, Selena, Duclert, Aymeric, Poirot, Laurent, Duchateau, Philippe, Juillerat, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727936/
https://www.ncbi.nlm.nih.gov/pubmed/34510816
http://dx.doi.org/10.1002/2211-5463.13292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727936/
https://www.ncbi.nlm.nih.gov/pubmed/34510816
http://dx.doi.org/10.1002/2211-5463.13292

Ejemplares similares