Identification and characterization of a novel glutaminase inhibitor

In humans, there are two forms of glutaminase (GLS), designated GLS1 and GLS2. These enzymes catalyse the conversion of glutamine to glutamate. GLS1 exists as two isozymes: kidney glutaminase (KGA) and glutaminase C (GAC). Several GLS inhibitors have been identified, of which DON (6‐diazo‐5‐oxonorle...

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Detalles Bibliográficos
Autores principales: Cederkvist, Henning, Kolan, Shrikant S., Wik, Jonas Aakre, Sener, Zeynep, Skålhegg, Bjørn Steen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727943/
https://www.ncbi.nlm.nih.gov/pubmed/34698439
http://dx.doi.org/10.1002/2211-5463.13319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727943/
https://www.ncbi.nlm.nih.gov/pubmed/34698439
http://dx.doi.org/10.1002/2211-5463.13319

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