AAV expressing an mTOR‐inhibiting siRNA exhibits therapeutic potential in retinal vascular disorders by preserving endothelial integrity

Expanding on previous demonstrations of the therapeutic effects of adeno‐associated virus (AAV) carrying small‐hairpin RNA (shRNA) in downregulating the mechanistic target of rapamycin (mTOR) in in vivo retinal vascular disorders, vascular endothelial growth factor (VEGF)‐stimulated endothelial cell...

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Detalles Bibliográficos
Autores principales: Cha, Seho, Seo, Won‐il, Woo, Ha‐Na, Kim, Hee Jong, Lee, Steven Hyun Seung, Kim, Jin, Choi, Jun‐Sub, Park, Keerang, Lee, Joo Yong, Lee, Beom Jun, Lee, Heuiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727948/
https://www.ncbi.nlm.nih.gov/pubmed/34431239
http://dx.doi.org/10.1002/2211-5463.13281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727948/
https://www.ncbi.nlm.nih.gov/pubmed/34431239
http://dx.doi.org/10.1002/2211-5463.13281

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