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Efficient approaches for large-scale GWAS with genotype uncertainty

Association studies using genetic data from SNP-chip-based imputation or low-depth sequencing data provide a cost-efficient design for large-scale association studies. We explore methods for performing association studies applicable to such genetic data and investigate how using different priors whe...

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Detalles Bibliográficos
Autores principales: Jørsboe, Emil, Albrechtsen, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727990/
https://www.ncbi.nlm.nih.gov/pubmed/34865001
http://dx.doi.org/10.1093/g3journal/jkab385