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Efficient approaches for large-scale GWAS with genotype uncertainty
Association studies using genetic data from SNP-chip-based imputation or low-depth sequencing data provide a cost-efficient design for large-scale association studies. We explore methods for performing association studies applicable to such genetic data and investigate how using different priors whe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727990/ https://www.ncbi.nlm.nih.gov/pubmed/34865001 http://dx.doi.org/10.1093/g3journal/jkab385 |