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Case Report: Combination of Olaparib With Chemotherapy in a Patient With ATM-Deficient Colorectal Cancer

Poly-ADP ribose polymerase (PARP) inhibitors are constantly increasing in their indications for use as anti-cancer treatment in various neoplasms, the majority of which are linked with BRCA deficiency. Preclinical data support the investigation of PARP inhibitors in other neoplasms exhibiting “BRCAn...

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Detalles Bibliográficos
Autores principales: Papageorgiou, Georgios I., Fergadis, Evangelos, Skouteris, Nikos, Christakos, Evridiki, Tsakatikas, Sergios A., Lianos, Evangelos, Kosmas, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728007/
https://www.ncbi.nlm.nih.gov/pubmed/35004311
http://dx.doi.org/10.3389/fonc.2021.788809