Deep learning-based brain transcriptomic signatures associated with the neuropathological and clinical severity of Alzheimer’s disease

Brain tissue gene expression from donors with and without Alzheimer’s disease has been used to help inform the molecular changes associated with the development and potential treatment of this disorder. Here, we use a deep learning method to analyse RNA-seq data from 1114 brain donors from the Accel...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Chen, Kewei, Su, Yi, Reiman, Eric M., Dudley, Joel T., Readhead, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728025/
https://www.ncbi.nlm.nih.gov/pubmed/34993477
http://dx.doi.org/10.1093/braincomms/fcab293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728025/
https://www.ncbi.nlm.nih.gov/pubmed/34993477
http://dx.doi.org/10.1093/braincomms/fcab293

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