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Deep learning-based brain transcriptomic signatures associated with the neuropathological and clinical severity of Alzheimer’s disease
Brain tissue gene expression from donors with and without Alzheimer’s disease has been used to help inform the molecular changes associated with the development and potential treatment of this disorder. Here, we use a deep learning method to analyse RNA-seq data from 1114 brain donors from the Accel...
Autores principales: | Wang, Qi, Chen, Kewei, Su, Yi, Reiman, Eric M., Dudley, Joel T., Readhead, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728025/ https://www.ncbi.nlm.nih.gov/pubmed/34993477 http://dx.doi.org/10.1093/braincomms/fcab293 |
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