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Massively parallel analysis of human 3′ UTRs reveals that AU-rich element length and registration predict mRNA destabilization
AU-rich elements (AREs) are 3′ UTR cis-regulatory elements that regulate the stability of mRNAs. Consensus ARE motifs have been determined, but little is known about how differences in 3′ UTR sequences that conform to these motifs affect their function. Here, we use functional annotation of sequence...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728028/ https://www.ncbi.nlm.nih.gov/pubmed/34849835 http://dx.doi.org/10.1093/g3journal/jkab404 |