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Suppression of cdc13-2-associated senescence by pif1-m2 requires Ku-mediated telomerase recruitment

In Saccharomyces cerevisiae, recruitment of telomerase to telomeres requires an interaction between Cdc13, which binds single-stranded telomeric DNA, and the Est1 subunit of telomerase. A second pathway involving an interaction between the yKu complex and telomerase RNA (TLC1) contributes to telomer...

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Detalles Bibliográficos
Autores principales: Fekete-Szücs, Enikő, Rosas Bringas, Fernando R, Stinus, Sonia, Chang, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728030/
https://www.ncbi.nlm.nih.gov/pubmed/34751785
http://dx.doi.org/10.1093/g3journal/jkab360