The misuse of distributional assumptions in functional class scoring gene-set and pathway analysis

Gene-set analysis (GSA) is a standard procedure for exploring potential biological functions of a group of genes. The development of its methodology has been an active research topic in recent decades. Many GSA methods, when newly proposed, rely on simulation studies to evaluate their performance wi...

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Detalles Bibliográficos
Autores principales: Ho, Chi-Hsuan, Huang, Yu-Jyun, Lai, Ying-Ju, Mukherjee, Rajarshi, Hsiao, Chuhsing Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728032/
https://www.ncbi.nlm.nih.gov/pubmed/34791175
http://dx.doi.org/10.1093/g3journal/jkab365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728032/
https://www.ncbi.nlm.nih.gov/pubmed/34791175
http://dx.doi.org/10.1093/g3journal/jkab365

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