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SwissBioisostere 2021: updated structural, bioactivity and physicochemical data delivered by a reshaped web interface
At several stages of drug discovery, bioisosteric replacement is a common and efficient practice to find new bioactive chemotypes or to optimize series of molecules toward drug candidates. The critical steps consisting in selecting which molecular moiety should be replaced by which other chemical fr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728117/ https://www.ncbi.nlm.nih.gov/pubmed/34788840 http://dx.doi.org/10.1093/nar/gkab1047 |