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SwissBioisostere 2021: updated structural, bioactivity and physicochemical data delivered by a reshaped web interface

At several stages of drug discovery, bioisosteric replacement is a common and efficient practice to find new bioactive chemotypes or to optimize series of molecules toward drug candidates. The critical steps consisting in selecting which molecular moiety should be replaced by which other chemical fr...

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Detalles Bibliográficos
Autores principales: Cuozzo, Alessandro, Daina, Antoine, Perez, Marta A S, Michielin, Olivier, Zoete, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728117/
https://www.ncbi.nlm.nih.gov/pubmed/34788840
http://dx.doi.org/10.1093/nar/gkab1047

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