Antiviral antibody responses to systemic administration of an oncolytic RNA virus: the impact of standard concomitant anticancer chemotherapies

BACKGROUND: Oncolytic reovirus therapy for cancer induces a typical antiviral response to this RNA virus, including neutralizing antibodies. Concomitant treatment with cytotoxic chemotherapies has been hypothesized to improve the therapeutic potential of the virus. Chemotherapy side effects can incl...

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Detalles Bibliográficos
Autores principales: Roulstone, Victoria, Mansfield, David, Harris, Robert J, Twigger, Katie, White, Christine, de Bono, Johann, Spicer, James, Karagiannis, Sophia N, Vile, Richard, Pandha, Hardev, Melcher, Alan, Harrington, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728387/
https://www.ncbi.nlm.nih.gov/pubmed/34301814
http://dx.doi.org/10.1136/jitc-2021-002673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728387/
https://www.ncbi.nlm.nih.gov/pubmed/34301814
http://dx.doi.org/10.1136/jitc-2021-002673

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