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Antiviral antibody responses to systemic administration of an oncolytic RNA virus: the impact of standard concomitant anticancer chemotherapies
BACKGROUND: Oncolytic reovirus therapy for cancer induces a typical antiviral response to this RNA virus, including neutralizing antibodies. Concomitant treatment with cytotoxic chemotherapies has been hypothesized to improve the therapeutic potential of the virus. Chemotherapy side effects can incl...
Autores principales: | Roulstone, Victoria, Mansfield, David, Harris, Robert J, Twigger, Katie, White, Christine, de Bono, Johann, Spicer, James, Karagiannis, Sophia N, Vile, Richard, Pandha, Hardev, Melcher, Alan, Harrington, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728387/ https://www.ncbi.nlm.nih.gov/pubmed/34301814 http://dx.doi.org/10.1136/jitc-2021-002673 |
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