Loss of full-length pumilio 1 abrogates miRNA-221-induced gene p27 silencing-mediated cell proliferation in the heart

Upregulated expression of microRNA (miR)-221 is associated with downregulation of p27 and subsequent increased cell proliferation in a variety of human cancers. It is unknown whether miR-221 mimics could trigger neoplastic cellular proliferation. In vitro, we demonstrated miR-221 significantly downr...

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Detalles Bibliográficos
Autores principales: Zhou, Yue, Ng, Denise YuEn, Richards, Arthur Mark, Wang, Peipei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728526/
https://www.ncbi.nlm.nih.gov/pubmed/35036057
http://dx.doi.org/10.1016/j.omtn.2021.12.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728526/
https://www.ncbi.nlm.nih.gov/pubmed/35036057
http://dx.doi.org/10.1016/j.omtn.2021.12.012

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