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OTUB1 knockdown promotes apoptosis in melanoma cells by upregulating TRAIL expression

Melanoma, the most serious type of skin cancer, exhibits a high risk of metastasis. Although chemotherapeutic treatment for metastatic melanoma improves disease outcome and patient survival, some patients exhibit resistance or toxicity to the drug treatment regime. OTUB1 is a deubiquitinating enzyme...

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Detalles Bibliográficos
Autores principales: Lee, Bok-Soon, Kang, Sung Un, Huang, Mei, Kim, Yeon Soo, Lee, Young-Sun, Park, Jae-Yong, Kim, Chul-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728537/
https://www.ncbi.nlm.nih.gov/pubmed/34488924
http://dx.doi.org/10.5483/BMBRep.2021.54.12.033