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Precise control of mitophagy through ubiquitin proteasome system and deubiquitin proteases and their dysfunction in Parkinson’s disease

Parkinson’s disease (PD) is one of the most common neurodegenerative diseases in the elderly population and is caused by the loss of dopaminergic neurons. PD has been predominantly attributed to mitochondrial dysfunction. The structural alteration of α-synuclein triggers toxic oligomer formation in...

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Detalles Bibliográficos
Autores principales: Park, Ga Hyun, Park, Joon Hyung, Chung, Kwang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728543/
https://www.ncbi.nlm.nih.gov/pubmed/34674795
http://dx.doi.org/10.5483/BMBRep.2021.54.12.107