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Induction of autophagy via the ROS-dependent AMPK-mTOR pathway protects copper-induced spermatogenesis disorder

Copper (Cu) is a necessary micronutrient at lower concentration, while excessive Cu exposure or Cu homeostasis disorders can lead to toxicity. The mechanism of male reproductive toxicity induced by Cu is still unknown. This study aims to investigate whether autophagy plays an important role in coppe...

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Detalles Bibliográficos
Autores principales: Guo, Hongrui, Ouyang, Yujuan, Yin, Heng, Cui, Hengmin, Deng, Huidan, Liu, Huan, Jian, Zhijie, Fang, Jing, Zuo, Zhicai, Wang, Xun, Zhao, Ling, Zhu, Yanqiu, Geng, Yi, Ouyang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728583/
https://www.ncbi.nlm.nih.gov/pubmed/34979450
http://dx.doi.org/10.1016/j.redox.2021.102227