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MicroRNA‐181a restricts human γδ T cell differentiation by targeting Map3k2 and Notch2

γδ T cells are a conserved population of lymphocytes that contributes to anti‐tumor responses through its overt type 1 inflammatory and cytotoxic properties. We have previously shown that human γδ T cells acquire this profile upon stimulation with IL‐2 or IL‐15, in a differentiation process dependen...

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Detalles Bibliográficos
Autores principales: Gordino, Gisela, Costa‐Pereira, Sara, Corredeira, Patrícia, Alves, Patrícia, Costa, Luís, Gomes, Anita Q, Silva‐Santos, Bruno, Ribot, Julie C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728617/
https://www.ncbi.nlm.nih.gov/pubmed/34821000
http://dx.doi.org/10.15252/embr.202052234