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Precise Diabetic Wound Therapy: PLS Nanospheres Eliminate Senescent Cells via DPP4 Targeting and PARP1 Activation

Diabetic ulcers, a difficult problem faced by clinicians, are strongly associated with an increase in cellular senescence. Few empirical studies have focused on exploring a targeted strategy to cure diabetic wounds by eliminating senescent fibroblasts (SFs) and reducing side effects. In this study,...

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Detalles Bibliográficos
Autores principales: Zhao, Renliang, Jin, Xiangyun, Li, Ang, Xu, Bitong, Shen, Yifan, Wang, Wei, Huang, Jinghuan, Zhang, Yadong, Li, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728814/
https://www.ncbi.nlm.nih.gov/pubmed/34738744
http://dx.doi.org/10.1002/advs.202104128