Citrate Promotes Excessive Lipid Biosynthesis and Senescence in Tumor Cells for Tumor Therapy

Metabolic disorder is one of the hallmarks of cancers, and reprogramming of metabolism is becoming a novel strategy for cancer treatment. Citrate is a key metabolite and critical metabolic regulator linking glycolysis and lipid metabolism in cellular energy homeostasis. Here it is reported that citr...

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Detalles Bibliográficos
Autores principales: Zhao, Yangjing, Liu, Xia, Si, Fusheng, Huang, Lan, Gao, Aiqin, Lin, Wenli, Hoft, Daniel F., Shao, Qixiang, Peng, Guangyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728847/
https://www.ncbi.nlm.nih.gov/pubmed/34747157
http://dx.doi.org/10.1002/advs.202101553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728847/
https://www.ncbi.nlm.nih.gov/pubmed/34747157
http://dx.doi.org/10.1002/advs.202101553

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