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The Tyrosine Kinase Tec Regulates Effector Th17 Differentiation, Pathogenicity, and Plasticity in T-Cell-Driven Intestinal Inflammation

T helper (Th) 17 cells are not only key in controlling infections mediated by extracellular bacteria and fungi but are also triggering autoimmune responses. Th17 cells comprise heterogeneous subsets, some with pathogenic functions. They can cease to secrete their hallmark cytokine IL-17A and even co...

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Detalles Bibliográficos
Autores principales: Sandner, Lisa, Alteneder, Marlis, Zhu, Ci, Hladik, Anastasiya, Högler, Sandra, Rica, Ramona, Van Greuningen, Lars W., Sharif, Omar, Sakaguchi, Shinya, Knapp, Sylvia, Kenner, Lukas, Trauner, Michael, Ellmeier, Wilfried, Boucheron, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728872/
https://www.ncbi.nlm.nih.gov/pubmed/35003062
http://dx.doi.org/10.3389/fimmu.2021.750466