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Sensei: how many samples to tell a change in cell type abundance?

Cellular heterogeneity underlies cancer evolution and metastasis. Advances in single-cell technologies such as single-cell RNA sequencing and mass cytometry have enabled interrogation of cell type-specific expression profiles and abundance across heterogeneous cancer samples obtained from clinical t...

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Detalles Bibliográficos
Autores principales: Liang, Shaoheng, Willis, Jason, Dou, Jinzhuang, Mohanty, Vakul, Huang, Yuefan, Vilar, Eduardo, Chen, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728970/
https://www.ncbi.nlm.nih.gov/pubmed/34983369
http://dx.doi.org/10.1186/s12859-021-04526-5