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Oral administration of TiO(2) nanoparticles during early life impacts cardiac and neurobehavioral performance and metabolite profile in an age- and sex-related manner

BACKGROUND: Nanoparticles (NPs) are increasingly incorporated in everyday products. To investigate the effects of early life exposure to orally ingested TiO(2) NP, male and female Sprague–Dawley rat pups received four consecutive daily doses of 10 mg/kg body weight TiO(2) NP (diameter: 21 ± 5 nm) or...

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Detalles Bibliográficos
Autores principales: Mortensen, Ninell P., Pathmasiri, Wimal, Snyder, Rodney W., Caffaro, Maria Moreno, Watson, Scott L., Patel, Purvi R., Beeravalli, Lakshmi, Prattipati, Sharmista, Aravamudhan, Shyam, Sumner, Susan J., Fennell, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728993/
https://www.ncbi.nlm.nih.gov/pubmed/34986857
http://dx.doi.org/10.1186/s12989-021-00444-9