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Naturally acquired antibody response to a Plasmodium falciparum chimeric vaccine candidate GMZ2.6c and its components (MSP-3, GLURP, and Pfs48/45) in individuals living in Brazilian malaria-endemic areas

BACKGROUND: The GMZ2.6c malaria vaccine candidate is a multi-stage Plasmodium falciparum chimeric protein which contains a fragment of the sexual-stage Pfs48/45-6C protein genetically fused to GMZ2, a fusion protein of GLURP and MSP-3, that has been shown to be well tolerated, safe and immunogenic i...

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Detalles Bibliográficos
Autores principales: Baptista, Barbara Oliveira, de Souza, Ana Beatriz Lopes, Riccio, Evelyn Kety Pratt, Bianco-Junior, Cesare, Totino, Paulo Renato Rivas, Martins da Silva, João Hermínio, Theisen, Michael, Singh, Susheel Kumar, Amoah, Linda Eva, Ribeiro-Alves, Marcelo, Souza, Rodrigo Medeiros, Lima-Junior, Josué Costa, Daniel-Ribeiro, Cláudio Tadeu, Pratt-Riccio, Lilian Rose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729018/
https://www.ncbi.nlm.nih.gov/pubmed/34983540
http://dx.doi.org/10.1186/s12936-021-04020-6