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Regulation of fatty acid desaturase- and immunity gene-expression by mbk-1/DYRK1A in Caenorhabditis elegans

BACKGROUND: In the nematode Caenorhabditis elegans, longevity in response to germline ablation, but not in response to reduced insulin/IGF1-like signaling, is strongly dependent on the conserved protein kinase minibrain-related kinase 1 (MBK-1). In humans, the MBK-1 ortholog DYRK1A is associated wit...

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Detalles Bibliográficos
Autores principales: Mack, Hildegard I. D., Kremer, Jennifer, Albertini, Eva, Mack, Elisabeth K. M., Jansen-Dürr, Pidder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729107/
https://www.ncbi.nlm.nih.gov/pubmed/34983389
http://dx.doi.org/10.1186/s12864-021-08176-y