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Offspring production of haploid spermatid-like cells derived from mouse female germline stem cells with chromatin condensation

BACKGROUND: During male meiosis, the Y chromosome can form perfect pairing with the X chromosome. However, it is unclear whether mammalian Female germline stem cells (FGSCs) without a Y chromosome can transdifferentiate into functional haploid spermatid-like cells (SLCs). RESULTS: We found that sper...

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Detalles Bibliográficos
Autores principales: Hu, Xiaopeng, Wang, Hu, Tian, Geng. G., Hou, Changliang, Xu, Bo, Zhao, Xinyan, Zhao, Yongqiang, Fang, Qian, Li, Xinyue, He, Lin, Chen, Xuejin, Li, Shangang, Wu, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729121/
https://www.ncbi.nlm.nih.gov/pubmed/34983631
http://dx.doi.org/10.1186/s13578-021-00697-z