Synthesis and preliminary evaluation of octreotate conjugates of bioactive synthetic amatoxins for targeting somatostatin receptor (sstr2) expressing cells

Targeted cancer therapy represents a paradigm-shifting approach that aims to deliver a toxic payload selectively to target-expressing cells thereby sparing normal tissues the off-target effects associated with traditional chemotherapeutics. Since most targeted constructs rely on standard microtubule...

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Detalles Bibliográficos
Autores principales: Pryyma, Alla, Matinkhoo, Kaveh, Bu, Yong Jia, Merkens, Helen, Zhang, Zhengxing, Bénard, Francois, Perrin, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729174/
https://www.ncbi.nlm.nih.gov/pubmed/35128410
http://dx.doi.org/10.1039/d1cb00036e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729174/
https://www.ncbi.nlm.nih.gov/pubmed/35128410
http://dx.doi.org/10.1039/d1cb00036e

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