Inhibition of SC4MOL and HSD17B7 shifts cellular sterol composition and promotes oligodendrocyte formation

While the cholesterol biosynthesis pathway has been extensively studied, recent work has forged new links between inhibition of specific sterol pathway enzymes, accumulation of their unique sterol substrates, and biological areas as diverse as cancer, immunology, and neurodegenerative disease. We re...

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Detalles Bibliográficos
Autores principales: Pleshinger, Matthew J, Friedrich, Ryan M., Hubler, Zita, Rivera-León, Adrianna M., Gao, Farrah, Yan, David, Sax, Joel L., Srinivasan, Ramya, Bederman, Ilya, Shick, H. Elizabeth, Tesar, Paul J., Adams, Drew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729178/
https://www.ncbi.nlm.nih.gov/pubmed/35128409
http://dx.doi.org/10.1039/d1cb00145k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729178/
https://www.ncbi.nlm.nih.gov/pubmed/35128409
http://dx.doi.org/10.1039/d1cb00145k

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