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Macrocyclic DNA-encoded chemical libraries: a historical perspective
While macrocyclic peptides are extensively researched for therapeutically relevant protein targets, DNA-encoded chemical libraries (DELs) are developed at a quick pace to discover novel small molecule binders. The combination of both fields has been explored since 2004 and the number of macrocyclic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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RSC
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729180/ https://www.ncbi.nlm.nih.gov/pubmed/35128404 http://dx.doi.org/10.1039/d1cb00161b |