Elevated Cerebrospinal Fluid Anti-CD4 Autoantibody Levels in HIV Associate with Neuroinflammation

The mechanisms of persistent central nervous system (CNS) inflammation in people with HIV (PWH) despite effective antiretroviral therapy (ART) are not fully understood. We have recently shown that plasma anti-CD4 IgGs contribute to poor CD4(+) T cell recovery during suppressive ART via antibody-medi...

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Detalles Bibliográficos
Autores principales: Cheng, Da, Luo, Zhenwu, Fu, Xiaoyu, Stephenson, Sophie, Di Germanio, Clara, Norris, Philip J., Fuchs, Dietmar, Ndhlovu, Lishomwa C., Li, Quan-zhen, Zetterberg, Henrik, Gisslen, Magnus, Price, Richard W., Peng, Shifang, Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729763/
https://www.ncbi.nlm.nih.gov/pubmed/34985329
http://dx.doi.org/10.1128/spectrum.01975-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729763/
https://www.ncbi.nlm.nih.gov/pubmed/34985329
http://dx.doi.org/10.1128/spectrum.01975-21

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