Cargando…
Elevated Cerebrospinal Fluid Anti-CD4 Autoantibody Levels in HIV Associate with Neuroinflammation
The mechanisms of persistent central nervous system (CNS) inflammation in people with HIV (PWH) despite effective antiretroviral therapy (ART) are not fully understood. We have recently shown that plasma anti-CD4 IgGs contribute to poor CD4(+) T cell recovery during suppressive ART via antibody-medi...
Autores principales: | Cheng, Da, Luo, Zhenwu, Fu, Xiaoyu, Stephenson, Sophie, Di Germanio, Clara, Norris, Philip J., Fuchs, Dietmar, Ndhlovu, Lishomwa C., Li, Quan-zhen, Zetterberg, Henrik, Gisslen, Magnus, Price, Richard W., Peng, Shifang, Jiang, Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729763/ https://www.ncbi.nlm.nih.gov/pubmed/34985329 http://dx.doi.org/10.1128/spectrum.01975-21 |
Ejemplares similares
-
Cerebrospinal fluid soluble CD30 elevation despite suppressive antiretroviral therapy in individuals living with HIV-1
por: Peluso, Michael J, et al.
Publicado: (2020) -
Compartmentalization of cerebrospinal fluid inflammation across the spectrum of untreated HIV-1 infection, central nervous system injury and viral suppression
por: Gisslen, Magnus, et al.
Publicado: (2021) -
Cerebrospinal fluid viral breakthrough in two HIV-infected subjects on darunavir/ritonavir monotherapy
por: Gisslén, Magnus, et al.
Publicado: (2012) -
Cerebrospinal Fluid Concentrations of the Synaptic Marker Neurogranin in Neuro-HIV and Other Neurological Disorders
por: Yilmaz, Aylin, et al.
Publicado: (2019) -
Cerebrospinal Fluid (CSF) Neuronal Biomarkers across the Spectrum of HIV Infection: Hierarchy of Injury and Detection
por: Peterson, Julia, et al.
Publicado: (2014)