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The endoplasmic reticulum–plasma membrane tethering protein TMEM24 is a regulator of cellular Ca(2+) homeostasis
Endoplasmic reticulum (ER)–plasma membrane (PM) contacts are sites of lipid exchange and Ca(2+) transport, and both lipid transport proteins and Ca(2+) channels specifically accumulate at these locations. In pancreatic β-cells, both lipid and Ca(2+) signaling are essential for insulin secretion. The...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729788/ https://www.ncbi.nlm.nih.gov/pubmed/34821358 http://dx.doi.org/10.1242/jcs.259073 |