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Determinants for intrinsically disordered protein recruitment into phase-separated protein condensates

Multivalent interactions between amino acid residues of intrinsically disordered proteins (IDPs) drive phase separation of these proteins into liquid condensates, forming various membrane-less organelles in cells. These interactions between often biased residues of IDPs are also likely involved in s...

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Detalles Bibliográficos
Autores principales: Jo, Yongsang, Jang, Jinyoung, Song, Daesun, Park, Hyoin, Jung, Yongwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729795/
https://www.ncbi.nlm.nih.gov/pubmed/35126984
http://dx.doi.org/10.1039/d1sc05672g