Cargando…

Determinants for intrinsically disordered protein recruitment into phase-separated protein condensates

Multivalent interactions between amino acid residues of intrinsically disordered proteins (IDPs) drive phase separation of these proteins into liquid condensates, forming various membrane-less organelles in cells. These interactions between often biased residues of IDPs are also likely involved in s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jo, Yongsang, Jang, Jinyoung, Song, Daesun, Park, Hyoin, Jung, Yongwon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729795/ https://www.ncbi.nlm.nih.gov/pubmed/35126984 http://dx.doi.org/10.1039/d1sc05672g

Ejemplares similares

Interplay between intrinsically disordered proteins inside membraneless protein liquid droplets
por: Jo, Yongsang, et al.
Publicado: (2019)

Behavior control of membrane-less protein liquid condensates with metal ion-induced phase separation
por: Hong, Kibeom, et al.
Publicado: (2020)

Client proximity enhancement inside cellular membrane-less compartments governed by client-compartment interactions
por: Song, Daesun, et al.
Publicado: (2020)

Fabrication of rigidity and space variable protein oligomers with two peptide linkers
por: Choi, Hyeokjune, et al.
Publicado: (2019)

Lipid coated protein condensates as stable protocells with selective uptake abilities for biomolecules
por: Son, Juyoung, et al.
Publicado: (2022)

Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins
por: Lee, Chih-Yung S, et al.
Publicado: (2020)

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
por: Harmon, Tyler S, et al.
Publicado: (2017)

Intrinsically disordered plant protein PARCL colocalizes with RNA in phase-separated condensates whose formation can be regulated by mutating the PLD
por: Ostendorp, Anna, et al.
Publicado: (2022)

Phase Separation of Intrinsically Disordered Nucleolar Proteins Relate to Localization and Function
por: Guillen-Chable, Francisco, et al.
Publicado: (2021)

Comparison of Biomolecular Condensate Localization and Protein Phase Separation Predictors
por: Kuechler, Erich R., et al.
Publicado: (2023)

Valence-controlled protein conjugation on nanoparticles via re-arrangeable multivalent interactions of tandem repeat protein chains
por: Choi, Hyeongjoo, et al.
Publicado: (2022)

Relevance of Electrostatic Charges in Compactness, Aggregation, and Phase Separation of Intrinsically Disordered Proteins
por: Bianchi, Greta, et al.
Publicado: (2020)

Intrinsically disordered proteins access a range of hysteretic phase separation behaviors
por: Garcia Quiroz, Felipe, et al.
Publicado: (2019)

Phase separation driven by interchangeable properties in the intrinsically disordered regions of protein paralogs
por: Chiu, Shih-Hui, et al.
Publicado: (2022)

Liquid–Liquid Phase Separation Modifies the Dynamic Properties of Intrinsically Disordered Proteins
por: Guseva, Serafima, et al.
Publicado: (2023)

Ionic polypeptide tags for protein phase separation
por: Kapelner, Rachel A., et al.
Publicado: (2019)

Conformational Dynamics of Intrinsically Disordered Proteins Regulate Biomolecular Condensate Chemistry
por: Abyzov, Anton, et al.
Publicado: (2022)

Protein Condensate Formation via Controlled Multimerization of Intrinsically Disordered Sequences
por: Garabedian, Mikael V., et al.
Publicado: (2022)

Sequence variations of phase-separating proteins and resources for studying biomolecular condensates: Resources for studying biomolecular condensates
por: Guo, Gaigai, et al.
Publicado: (2023)

Expansion of Intrinsically Disordered Proteins Increases the Range of Stability of Liquid–Liquid Phase Separation
por: Garaizar, Adiran, et al.
Publicado: (2020)

Conformational editing of intrinsically disordered protein by α-methylation
por: Bauer, Valentin, et al.
Publicado: (2020)

Thermodynamic forces from protein and water govern condensate formation of an intrinsically disordered protein domain
por: Mukherjee, Saumyak, et al.
Publicado: (2023)

Condensation of pericentrin proteins in human cells illuminates phase separation in centrosome assembly
por: Jiang, Xueer, et al.
Publicado: (2021)

Proximity editing to identify RNAs in phase-separated RNA binding protein condensates
por: Zhou, Guilong, et al.
Publicado: (2021)

The impact of O-glycan chemistry on the stability of intrinsically disordered proteins
por: Prates, Erica T., et al.
Publicado: (2018)

Proteins with Intrinsically Disordered Domains Are Preferentially Recruited to Polyglutamine Aggregates
por: Wear, Maggie P., et al.
Publicado: (2015)

The importance of the compact disordered state in the fuzzy interactions between intrinsically disordered proteins
por: Wang, Dan, et al.
Publicado: (2022)

Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs
por: Lin, Yuan, et al.
Publicado: (2017)

Thermodynamic and sequential characteristics of phase separation and droplet formation for an intrinsically disordered region/protein ensemble
por: Chu, Wen-Ting, et al.
Publicado: (2021)

The Role of Intrinsically Disordered Proteins in Liquid–Liquid Phase Separation during Calcium Carbonate Biomineralization
por: Tarczewska, Aneta, et al.
Publicado: (2022)

Dynamic Structural Changes and Thermodynamics in Phase Separation Processes of an Intrinsically Disordered–Ordered Protein Model
por: Lüdeke, Steffen, et al.
Publicado: (2021)

In-Silico Analysis of pH-Dependent Liquid-Liquid Phase Separation in Intrinsically Disordered Proteins
por: Pintado-Grima, Carlos, et al.
Publicado: (2022)

Intrinsically disordered regions that drive phase separation form a robustly distinct protein class
por: Ibrahim, Ayyam Y., et al.
Publicado: (2022)

High order assembly of multiple protein cages with homogeneous sizes and shapes via limited cage surface engineering
por: Oh, Hyeok Jin, et al.
Publicado: (2022)

Structural Proteomics Methods to Interrogate the Conformations and Dynamics of Intrinsically Disordered Proteins
por: Beveridge, Rebecca, et al.
Publicado: (2021)

Folding and self-assembly of short intrinsically disordered peptides and protein regions
por: Argudo, Pablo G., et al.
Publicado: (2021)

Through the lens of phase separation: intrinsically unstructured protein and chromatin looping
por: Cai, Ling, et al.
Publicado: (2023)

RNA is a critical element for the sizing and the composition of phase-separated RNA–protein condensates
por: Garcia-Jove Navarro, Marina, et al.
Publicado: (2019)

Transcriptional condensates and phase separation: condensing information across scales and mechanisms
por: Demmerle, Justin, et al.
Publicado: (2023)

Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3
por: Smith, Jarrett, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_nggn80nn4lgra7p9vhsnjsanhr