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De novo generation of a bright blue fluorophore from 2-oxoglutarate in biological samples

We discovered the generation of a new bright blue fluorophore from a particular type of amine and 2-oxoglutarate (2-OG) under mild conditions without any chemical additives. Two β-aminoethylamine molecules and three 2-OG molecules form an unprecedented 2-pyridone structure with a fused γ-lactam ring...

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Detalles Bibliográficos
Autores principales: Kim, Yumin, Kang, Sangyoon, Lee, Byung Hun, Song, Youngjun, Kang, Sunah, Park, Hye Yoon, Lee, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729799/
https://www.ncbi.nlm.nih.gov/pubmed/35126969
http://dx.doi.org/10.1039/d1sc05808h