Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach

The four Janus kinase (JAK) proteins and seven signal transducer and activator of transcription (STAT) transcription factors mediate intracellular signal transduction downstream of cytokine receptors, which are implicated in the pathology of autoimmune, allergic and inflammatory diseases. Developmen...

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Detalles Bibliográficos
Autores principales: Tanaka, Yoshiya, Luo, Yiming, O’Shea, John J., Nakayamada, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730299/
https://www.ncbi.nlm.nih.gov/pubmed/34987201
http://dx.doi.org/10.1038/s41584-021-00726-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730299/
https://www.ncbi.nlm.nih.gov/pubmed/34987201
http://dx.doi.org/10.1038/s41584-021-00726-8

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