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The impact of maternal age on gene expression during the GV to MII transition in euploid human oocytes

STUDY QUESTION: Are there age-related differences in gene expression during the germinal vesicle (GV) to metaphase II (MII) stage transition in euploid human oocytes? SUMMARY ANSWER: A decrease in mitochondrial-related transcripts from GV to MII oocytes was observed, with a much greater reduction in...

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Detalles Bibliográficos
Autores principales: Ntostis, P, Iles, D, Kokkali, G, Vaxevanoglou, T, Kanavakis, E, Pantou, A, Huntriss, J, Pantos, K, Picton, H M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730309/
https://www.ncbi.nlm.nih.gov/pubmed/34755188
http://dx.doi.org/10.1093/humrep/deab226