DNMT1 regulates the timing of DNA methylation by DNMT3 in an enzymatic activity-dependent manner in mouse embryonic stem cells

DNA methylation (DNAme; 5-methylcytosine, 5mC) plays an essential role in mammalian development, and the 5mC profile is regulated by a balance of opposing enzymatic activities: DNA methyltransferases (DNMTs) and Ten-eleven translocation dioxygenases (TETs). In mouse embryonic stem cells (ESCs), de n...

Descripción completa

Detalles Bibliográficos
Autores principales: Ito, Takamasa, Kubiura-Ichimaru, Musashi, Murakami, Yuri, Bogutz, Aaron B., Lefebvre, Louis, Suetake, Isao, Tajima, Shoji, Tada, Masako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730390/
https://www.ncbi.nlm.nih.gov/pubmed/34986190
http://dx.doi.org/10.1371/journal.pone.0262277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730390/
https://www.ncbi.nlm.nih.gov/pubmed/34986190
http://dx.doi.org/10.1371/journal.pone.0262277

Ejemplares similares